133991-63-6

Basic information

• Product Name: Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)-
• Synonyms: Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)-;CCMMQGHLQQKWOY-NGVSTBRYSA-N
• CAS NO: 133991-63-6
• Molecular Formula: C23H30O7
• Molecular Weight: 418.4801
• Mol File: 133991-63-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)-(CAS DataBase Reference)
• NIST Chemistry Reference: Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)-(133991-63-6)
• EPA Substance Registry System: Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)-(133991-63-6)

Safety Data

• Hazardous Substances Data: 133991-63-6(Hazardous Substances Data)

Usage

Description

Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)is a chemical compound derived from Loteprednol Etabonate (L471400), which is an ophthalmic corticosteroid. Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)is characterized by its unique molecular structure, featuring a 17-carboxylic acid group, an ethoxycarbonyloxy group, and hydroxy and oxo groups at specific positions.

Uses

Used in Pharmaceutical Industry:
Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)is used as an active pharmaceutical ingredient for the development of ophthalmic corticosteroids. Its application is primarily due to its anti-inflammatory and immunosuppressive properties, which are beneficial in treating various eye conditions such as uveitis, iritis, and postoperative inflammation following ocular surgery.
Used in Ophthalmology:
In the field of ophthalmology, Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, (11β,17α)is used as a therapeutic agent for managing ocular inflammation and reducing the risk of vision loss associated with certain eye diseases. Its application in this field is attributed to its ability to modulate the immune response and alleviate inflammation in the eye, thus providing relief and promoting healing.