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5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite, which is an essential vitamin B9 derivative. It plays a crucial role in the synthesis of methionine from homocysteine by donating a methyl group. 5-Methyltetrahydrofolicacid 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotopically labeled version of this vitamin, where all five glutamate carbons are replaced by 13C, making it a valuable tool for accurate data interpretation in analytical chemistry.

134-35-0

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134-35-0 Usage

Uses

Used in Analytical Chemistry:
5-Methyltetrahydrofolic acid is used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by liquid chromatography-mass spectrometry (LC-MS). This application ensures precise and reliable measurements, which is vital for quality control and research purposes.
Used in Metabolism and Health:
As a metabolite of folic acid, 5-Methyltetrahydrofolic acid plays a significant role in various biological processes, including the synthesis of methionine from homocysteine. This conversion is essential for maintaining proper methylation patterns in the body, which is crucial for overall health and the prevention of certain diseases.
Used in Antioxidant and DNA Protection:
5-Methyltetrahydrofolic acid also functions as an antioxidant, inhibiting photosensitization reactions and preventing strand breaks in DNA. This protective role is vital for maintaining the integrity of genetic material and supporting the body's natural defense mechanisms against oxidative stress and damage.

Supplements

5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

Mechanism of Action

Prefolic A, also known as 5-Methyltetrahydrofolate, is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. Methyl folate is an active metabolite of folic acid. Vitamin supplement in health care products.

Shipping & Storage Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Stored in dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Shelf Life can be more than 2 years if stored properly.

Check Digit Verification of cas no

The CAS Registry Mumber 134-35-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 134-35:
(5*1)+(4*3)+(3*4)+(2*3)+(1*5)=40
40 % 10 = 0
So 134-35-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12?,13-/m0/s1

134-35-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyltetrahydrofolic acid

1.2 Other means of identification

Product number -
Other names MethylFolate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:134-35-0 SDS

134-35-0Upstream product

134-35-0Downstream Products

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