134005-63-3

Upstream product

• 134005-59-7 C₁₉H₃₇AlOSi 
• 117254-07-6 (4R)-2-(N,N-diethylamino)methyl-4-(t-butyldimethylsiloxy)-cyclopent-2-en-1-ol 
• 105803-39-2 (S)-3-<(tert-Butyldimethylsilyl)oxy>-3-cyclohexyl-1-propyne 
• 96-10-6 diethyl aluminiumcholoride 

Downstream Products

• 749245-13-4 3, 4, 5, 16, 17, 18, 19, 20-octanol-2, 6-inter-m-phenylene-15-cyclohexyl-13, 14-didehydro-PGE₁ ethyl ester 11, 15-bis(tert-butyldimethylsilyl ether) 
• 749245-63-4 6-thia-3, 4, 5, 16, 17, 18, 19, 20-octanol-2, 6-inter-m-phenylene-15-cyclohexyl-PGE₁ ethyl ester 11, 15-bis(tert-butyldimethylsilyl ether) 
• 647028-35-1 2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGE₁ 11,15-bis(tert-butyldimethylsilyl ether) 

Relevant academic research and scientific papers

PROSTAGLANDIN DERIVATIVES

A prostaglandin derivative represented by the formula (wherein X is a halogen atom; Y is ethylene group, vinylene group or ethylylene group; Z is a group represented by -(CH2)m-, -O(CH2)n- or -S(O)p-(CH2/s

PROSTAGLANDIN DERIVATIVES

A prostaglandin derivative represented by Formula (I) : wherein X is a halogen atom in the α- or β-substitution, Y is an ethylene group, a vinylene group or an ethynylene group, R1 is a C3-10 cycloalkyl group, a C3-10 cycl

PROSTAGLANDIN DERIVATIVES

A prostaglandin derivative represented by the formula: wherein X is a halogen atom, R1 is a hydrogen atom, a C1-10 alkyl group or a C3-10 cycloalkyl group, m is an integer of 0 to 5, and Y is a group represented by the for

Prostaglandin derivatives

A prostaglandin derivative represented by the formula: STR1 wherein X is halogen atom R1 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, and R2 is a cycloalkyl group having 3 to 10 carbon atoms, a cycloalkylmethyl gr

Prostaglandin derivatives

A prostaglandin derivative represented by formula STR1 wherein R1 represents a hydrogen atom or a C1 -C6 alkyl group, and R2 represents a cyclohexyl group or a cyclopentylmethyl group. This compound has physiolo

Prostaglandin derivatives

Object Novel PG derivatives having an excellent platelet aggregation inhibition activity are provided. Construction Prostaglandin derivatives represented by formula: STR1 and salts thereof.

Highly Efficient Synthesis of 13-Dehydroprostaglandins by 1,4-Addition Reaction of Alkynyl ω Side-Chain Unit onto Cyclopentenone Framework

Optically active 2-((diethylamino)methyl)-4-siloxy-2-cyclopentenone (2) reacts with a diethyl(3-(tert-butyldimethylsiloxy)-1-alkynyl)aluminum compound via 1,4-addition pathway to afford the enone 5, useful intermediate for synthesis of PGs via two-component coupling process, in excellent yield, thus making it easy to synthesize 13-dehydro-PGs.