134009-09-9 Usage
General Description
The chemical compound "(D-HIS(BZL)6,PRO-NHET9)-LHRH (4-9)" is a synthetic peptide derivative of luteinizing hormone-releasing hormone (LHRH) designed to suppress the production of hormones that stimulate ovulation and the release of eggs from the ovaries. (D-HIS(BZL)6,PRO-NHET9)-LHRH (4-9) contains modifications to the amino acid sequence of natural LHRH, including substitutions of specific amino acids such as histidine (HIS) and proline (PRO). These modifications enhance the stability and potency of the compound, making it a promising candidate for the treatment of hormone-sensitive conditions such as prostate cancer and breast cancer.("(D-HIS(BZL)6,PRO-NHET9)-LHRH (4-9)")
Check Digit Verification of cas no
The CAS Registry Mumber 134009-09-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,0,0 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 134009-09:
(8*1)+(7*3)+(6*4)+(5*0)+(4*0)+(3*9)+(2*0)+(1*9)=89
89 % 10 = 9
So 134009-09-9 is a valid CAS Registry Number.
134009-09-9Relevant articles and documents
Characterization of the solution degradation products of histrelin, a gonadotropin releasing hormone (LH/RH) agonist
Oyler,Naldi,Lloyd,Graden,Shaw,Cotter
, p. 271 - 275 (1991)
The degradation products of histrelin (1, Glu-His-Trp-Ser-Tyr-(D-N(im)-bzl-His)-Leu-Arg-Pro-NHEt) were determined in aqueous solution at pH 5.4 and 87°C over an 18-day period (47% degradation). These degradation products (2-5) resulted from the cleavage of Glu-His and Trp-Ser peptide bonds, His-Trp diketopiperazine formation, and racemization of serine and histidine residues.
