134029-54-2Relevant academic research and scientific papers
Novel B-ring modified combretastatin analogues: Syntheses and antineoplastic activity
Hatanaka, Toshihiro,Fujita, Koichi,Ohsumi, Koji,Nakagawa, Ryusuke,Fukuda, Yumiko,Nihei, Yukio,Suga, Yasuyo,Akiyama, Yukio,Tsuji, Takashi
, p. 3371 - 3374 (2007/10/03)
A series of B-ring modified combretastatin analogues were synthesized and their inhibitory activity against microtubule assembly, cytotoxic activity against Colon 26 adenocarcinoma cancer cell line were evaluated. Among these, pyridone derivative (19) showed strong antimitotic activity and cytotoxicity, along with excellent water-solubility.
Stilbene derivatives as anticancer agents
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, (2008/06/13)
The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can be utilized in a method of treating such cancers. Pharmaceu
Synthesis and Evaluation of Stilbene and Dihydrostilbene Derivatives as Potential Anticancer Agents That Inhibit Tubulin Polymerization
Cushman, Mark,Nagarathnam, Dhanapalan,Gopal, D.,Chakraborti, Asit K.,Lin, Chii M.,Hamel, Ernest
, p. 2579 - 2588 (2007/10/02)
An array of cis-, trans-, and dihydrostilbenes and some N-arylbenzylamines were synthesized and evaluated for their cytotoxicity in the five cancer cell cultures A-549 lung carcinoma, MCF-7 breast carcinoma, HT-29 colon adenocarcinoma, SKMEL-5 melanoma, a
