134079-94-0

Basic information

• Product Name: 2-amino-5,7-dihydro-5-oxo-4-p-tolyl-4H-furo[3,4-b]pyran-3-carbonitrile
• Synonyms: 2-amino-5,7-dihydro-5-oxo-4-p-tolyl-4H-furo[3,4-b]pyran-3-carbonitrile
• CAS NO: 134079-94-0
• Molecular Weight: 268.272
• Mol File: 134079-94-0.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-5,7-dihydro-5-oxo-4-p-tolyl-4H-furo[3,4-b]pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5,7-dihydro-5-oxo-4-p-tolyl-4H-furo[3,4-b]pyran-3-carbonitrile(134079-94-0)
• EPA Substance Registry System: 2-amino-5,7-dihydro-5-oxo-4-p-tolyl-4H-furo[3,4-b]pyran-3-carbonitrile(134079-94-0)

Safety Data

• Hazardous Substances Data: 134079-94-0(Hazardous Substances Data)

Upstream product

• 4971-56-6 tetrahydrofuran-2,4-dione 
• 104-87-0 4-methyl-benzaldehyde 
• 109-77-3 malononitrile 
• 2826-25-7 2-(4-methylbenzylidene)malononitrile 

Relevant articles and documents

Multicomponent synthesis of a new series of 4H-furo[3,4-b]pyrans, with iron(III) triflate as catalyst

We report the first efficient multicomponent reaction, catalyzed by iron(III) triflate, for synthesis of a new series of functionalized 4H-furo[3,4-b]pyran derivatives.

A Novel One-Step Synthesis of 4H-Furopyrans and a Transformation into a Difuropyridine

A simple one-step synthesis of 2-amino-4-aryl-5-oxo-4H-furopyran-3-carbonitriles 7 is described.It involves reaction of 2,4(3H,5H)-furandione (β-tetronic acid) (5) with arylmethylenemalononitriles 4 in basic medium.Some substituent effects are noted and the assignments of 13C-NMR spectra are discussed.Ring transformation of the furopyran 7a leads to the difuropyridine 9.Key Words: Furopyrans / Difuropyridine / β-Tetronic acid / Malononitriles, arylmethylene-