134099-34-6

Upstream product

• 401-85-4 α,α,α,3,5-pentafluorotoluene 
• 68-12-2 N,N-dimethyl-formamide 

Relevant academic research and scientific papers

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

PYRAZOLYL PYRIMIDINONE COMPOUNDS AS PDE2 INHIBITORS

The present invention is directed to pyrimidine carboxamide compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

Nuclear-fluorinated trifluoromethylbenzaldehydes

Process for the preparation of nuclear-fluorinated trifluoromethylbenzaldehydes from nuclear-chlorinated trifluoromethylbenzaldehydes, and new nuclear-fluorinated trifluoromethylbenzaldehydes.