134148-64-4

Upstream product

• 129718-00-9 6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-one 
• 103-71-9 phenyl isocyanate 

Downstream Products

• 134148-73-5 6-cyano-2,2-dimethyl-3-methoxy-4-phenylaminocarbonyl-2H-1-benzopyran 
• 135144-41-1 6-Cyano-2,2,4-trimethyl-3-oxo-chroman-4-carboxylic acid phenylamide 
• 135144-44-4 6-Cyano-4-fluoro-2,2-dimethyl-3-oxo-chroman-4-carboxylic acid phenylamide 
• 134148-65-5 (3S,4S)-6-Cyano-3-hydroxy-2,2-dimethyl-chroman-4-carbothioic acid phenylamide 
• 134148-65-5 (3R,4S)-6-Cyano-3-hydroxy-2,2-dimethyl-chroman-4-carbothioic acid phenylamide 
• 135144-43-3 3-acetoxy-N-acetyl-6-cyano-2,2-dimethyl-N-phenyl-2H-1-benzopyran-4-carboxamide 
• 134148-69-9 6-cyano-2,2-dimethyl-4-phenylaminocarbonyl-2H-1-benzopyran 

Relevant academic research and scientific papers

Benzopyran derivatives

Benzopyran derivatives represented by formula (I): [Figure] wherein X represents =O, =S, =N-Z (Z represents a lower alkyl group, etc.), or =CHNO2 ; Y represents a substituted amino group, an alkoxy group, an alkylthio group, etc., and R1, R2, R3, R4, R5,

Relaxant activity of 6-cyano-2,2-dimethyl-2H-1-benzopyran-4-carboxamides and -thiocarboxamides and their analogues in guinea pig trachealis

Structural modifications of the potassium channel activator cromakalim (1) are described in which the amide moiety at C-4 has been replaced by carboxamide and thiocarboxamide functions. Analogues in which the hydroxyl group at C-3 has been oxidized or rem

Benzopyran derivatives

A compound of formula (I): or, where appropriate, a pharmaceutically acceptable salt, ester or amide thereof, or a pharmaceutically acceptable solvate thereof, wherein:, X represents O or S;, Y represents N or N -O or a moiety CR7 wherein, Rsu