134162-63-3

Upstream product

• 134164-11-7 methyl 8-(p-chlorophenylsulfonamido)-4-[3-(pyridin-3-yl)propyl]-octanoate 
• 134235-78-2 CGS 22652 
• 134162-80-4 6-(p-chlorophenylsulfonamido)-2-[3-(pyridin-3-yl)propyl]-hexanal 
• 134162-75-7 diethyl (4-azidobutyl)<3-(3-pyridinyl)propyl>malonate 
• 144385-78-4 6-Amino-2-(3-pyridin-3-yl-propyl)-hexanoic acid 
• 144385-71-7 Methanesulfonic acid 4-(7-oxo-oxepan-4-yl)-butyl ester 
• 134164-08-2 5-(4-Azido-butyl)-oxepan-2-one 
• 134163-31-8 4-(4-hydroxybutyl)-ε-caprolactone 
• 144385-72-8 5-(4-Amino-butyl)-oxepan-2-one 
• 41038-63-5 3-(pyridin-3-yl)propyl bromide hydrobromide 
• 144409-93-8 methyl 8-<<(4-chlorophenyl)sulfonyl>amino>-4-<3-(3-pyridinyl)propyl>oct-2-enoate 
• 134162-78-0 ethyl 6-<<(4-chlorophenyl)sulfonyl>amino>-2-<3-(3-pyridinyl)propyl>hexanoate 
• 134163-34-1 methyl 8-<<(4-chlorophenyl)sulfonyl>amino>-4-(2-hydroxyethyl)octanoate 
• 134163-39-6 methyl 8-(p-chlorophenylsulfonamido)-4-(formylmethyl)-octanoate 

Downstream Products

• 134163-84-1 8-(p-chlorophenyl-sulfonamido)-4-[3-(pyridin-3-yl)propyl]octanenitrile 

Relevant academic research and scientific papers

Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 4. 8-[[(4-chlorophenyl)sulfonyl]amino]-4-(3-(3- pyridinyl)propyl)octanoic acid and analogs

The title compound (10a) and its analogs were synthesized and found to possess two activities, the inhibition of the biosynthesis of thromboxane A2 and antagonism of its receptors. The in vitro and in vivo profile of these compounds as thromboxane recepto

CERTAIN (ARYLSULFONAMIDO- AND IMIDAZOLYL-)-SUBSTITUTED CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND USE FOR SUPPRESSING THROMBOXANE ACTIVITY

The present invention is concerned with compounds of formula I STR1 wherein A, B, M, R, Ar and Het are as defined in the specification, pharmaceutically acceptable ester and amide derivatives thereof; N-oxides thereof, tetrazole derivatives thereof, and s

(Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity

Disclosed are the compounds of formula STR1 wherein A represents lower alkylene; B represents oxygen, sulfur, lower alkylene, lower alkylene interrupted by oxygen, sulfur, sulfinyl or sulfonyl, (oxy-, sulfinyl-, sulfonyl- or thio)-lower alkylene, lower al