134169-61-2

Upstream product

• 39038-42-1 3-(N,N-dimethylamino)-1-(3,4,5-trimethoxyphenyl)propan-1-one 
• 74-88-4 methyl iodide 

Downstream Products

• 134236-03-6 (-)-trans-(2S,5S)-2-<3-<((2R)-2-hydroxypropyl)sulfonyl>-4-n-propoxy-5-(benzyloxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134236-02-5 (-)-trans-(2S,5S)-2-<3-<((2S)-2-hydroxypropyl)sulfonyl>-4-n-propoxy-5-(benzyloxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134169-28-1 (-)-trans-(2S,5S)-2-<3-<((2R,S)-2-hydroxypropyl)-sulfonyl>-4-n-propyl-5-(benzyloxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134236-06-9 (-)-trans-(2S,5S)-2-<3-<((2R)-2-hydroxypropyl)sulfonyl>-4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134169-30-5 (-)-trans-(2S,5S)-2-<3-<((2S)-2-hydroxypropyl)sulfonyl>-4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 143395-23-7 (2S,5R)-2-(3-Benzyloxy-5-methanesulfonyl-4-propoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan 
• 134186-90-6 trans-2-(3-benzyloxy-4-propoxy-5-methylsulfonylphenyl)-5-(3,4,5-trimethoxyphenyl)-tetrahydrofuran 
• 134169-29-2 3-((R)-2-Hydroxy-propane-1-sulfonyl)-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-phenol 
• 134236-04-7 3-((S)-2-Hydroxy-propane-1-sulfonyl)-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-phenol 
• 143346-10-5 (R)-Methoxy-phenyl-acetic acid (R)-2-{3-benzyloxy-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzenesulfonyl}-1-methyl-ethyl ester 
• 143395-27-1 (R)-Methoxy-phenyl-acetic acid (S)-2-{3-benzyloxy-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzenesulfonyl}-1-methyl-ethyl ester 
• 134169-24-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<<<3-(dibenzyloxy)phosphoryl>oxy>propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134236-08-1 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(phosphonooxy)propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134186-92-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(1-morpholino)-n-propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 

Relevant academic research and scientific papers

CERTAIN 2,5-DIARYL TETRAHYDROFURANS AND ANALOGS THEREOF AS PAF ANTAGONISTS

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein R 4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group, Y is an alkyl or substituted alkyl group and R 6 is an alkoxy or a substituted alkoxy or alkyl group.

2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group, Y is an alkyl or substituted alkyl group, R6 is an alkyl or a substituted alkyl group and the substituents at positions 3, 4 or 5 are acyclic.