134176-20-8 Usage
General Description
(1alpha,6alpha,7alpha)-2-Oxobicyclo[4.1.0]heptane-7-carboxylic acid methyl ester is a chemical compound that is a methyl ester derivative of a bicyclic organic acid. It is known for its use in organic synthesis and as a building block in the preparation of various complex compounds. (1alpha,6alpha,7alpha)-2-Oxobicyclo[4.1.0]heptane-7-carboxylic acid methyl ester has a unique bicyclic structure with a ketone and carboxylic acid functional group, making it versatile for a wide range of chemical reactions and transformations. It is commonly used in pharmaceutical research and drug development due to its potential medicinal properties and biological activities. Researchers continue to explore the potential applications of this compound in various fields, including medicine, materials science, and chemical engineering.
Check Digit Verification of cas no
The CAS Registry Mumber 134176-20-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,1,7 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 134176-20:
(8*1)+(7*3)+(6*4)+(5*1)+(4*7)+(3*6)+(2*2)+(1*0)=108
108 % 10 = 8
So 134176-20-8 is a valid CAS Registry Number.
134176-20-8Relevant articles and documents
Platinum-Catalyzed α,β-Desaturation of Cyclic Ketones through Direct Metal–Enolate Formation
Chen, Ming,Dong, Guangbin
supporting information, p. 7956 - 7961 (2021/03/01)
The development of a platinum-catalyzed desaturation of cyclic ketones to their conjugated α,β-unsaturated counterparts is reported in this full article. A unique diene-platinum complex was identified to be an efficient catalyst, which enables direct metal-enolate formation. The reaction operates under mild conditions without using strong bases or acids. Good to excellent yields can be achieved for diverse and complex scaffolds. A wide range of functional groups, including those sensitive to acids, bases/nucleophiles, or palladium species, are tolerated, which represents a distinct feature from other known desaturation methods. Mechanistically, this platinum catalysis exhibits a fast and reversible α-deprotonation followed by a rate-determining β-hydrogen elimination process, which is different from the prior Pd-catalyzed desaturation method. Promising preliminary enantioselective desaturation using a chiral-diene-platinum complex has also been obtained.
