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134190-11-7

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134190-11-7 Usage

General Description

(D-HIS(BZL)6,PRO-NHET9)-LHRH (2-9) is a synthetic peptide hormone that mimics the activity of luteinizing hormone-releasing hormone (LHRH). It is a modified form of LHRH that has been altered to enhance its stability and potency. The peptide contains a D-HIS(BZL)6 residue, which is a modified form of the amino acid histidine, as well as a PRO-NHET9 residue, which is a modified form of the amino acid proline. These modifications help to improve the peptide's binding affinity and biological activity. (D-HIS(BZL)6,PRO-NHET9)-LHRH (2-9) has been studied for its potential use in the treatment of hormone-dependent conditions such as prostate cancer and breast cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 134190-11-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,1,9 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 134190-11:
(8*1)+(7*3)+(6*4)+(5*1)+(4*9)+(3*0)+(2*1)+(1*1)=97
97 % 10 = 7
So 134190-11-7 is a valid CAS Registry Number.

134190-11-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name His-Trp-Ser-Tyr-(D-Nim-bzl-His)-Leu-Arg-Pro-NHEt

1.2 Other means of identification

Product number -
Other names (D-His(Bzl)6,Pro-NHEt9)-LHRH (2-9), (Des-Pyr1)-Histrelin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:134190-11-7 SDS

134190-11-7Upstream product

134190-11-7Downstream Products

134190-11-7Relevant articles and documents

Characterization of the solution degradation products of histrelin, a gonadotropin releasing hormone (LH/RH) agonist

Oyler,Naldi,Lloyd,Graden,Shaw,Cotter

, p. 271 - 275 (2007/10/02)

The degradation products of histrelin (1, Glu-His-Trp-Ser-Tyr-(D-N(im)-bzl-His)-Leu-Arg-Pro-NHEt) were determined in aqueous solution at pH 5.4 and 87°C over an 18-day period (47% degradation). These degradation products (2-5) resulted from the cleavage of Glu-His and Trp-Ser peptide bonds, His-Trp diketopiperazine formation, and racemization of serine and histidine residues.

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