134240-37-2

Basic information

• Product Name: BENZYL-(3-METHOXY-BENZYL)-AMINE
• Synonyms: N-BENZYL-1-(3-METHOXYPHENYL)METHANAMINE;ZERENEX E/6027254;BENZYL-(3-METHOXY-BENZYL)-AMINE;N-[(3-methoxyphenyl)methyl]-1-phenylmethanamine
• CAS NO: 134240-37-2
• Molecular Formula: C₁₅H₁₇NO
• Molecular Weight: 227.3
• Mol File: 134240-37-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 345.6 °C at 760 mmHg
• Flash Point: 143.3 °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 6.1E-05mmHg at 25°C
• PKA: 8.66±0.20(Predicted)
• CAS DataBase Reference: BENZYL-(3-METHOXY-BENZYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL-(3-METHOXY-BENZYL)-AMINE(134240-37-2)
• EPA Substance Registry System: BENZYL-(3-METHOXY-BENZYL)-AMINE(134240-37-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 134240-37-2(Hazardous Substances Data)

Usage

General Description

Benzyl-(3-methoxy-benzyl)-amine is a chemical compound consisting of a benzyl group attached to a 3-methoxy-benzyl group through an amine linkage. It is used in organic synthesis and pharmaceutical research as a precursor in the manufacture of various pharmaceuticals. The compound has potential applications in the development of new drugs and has been studied for its potential medicinal properties. Its structure and properties make it a valuable building block in the synthesis of a wide range of biologically active molecules. Additionally, it may have uses in the development of new materials and in chemical research.

InChI:InChI=1/C15H17NO/c1-17-15-9-5-8-14(10-15)12-16-11-13-6-3-2-4-7-13/h2-10,16H,11-12H2,1H3/p+1

Upstream product

• 74083-63-9 (E)-N-(3-methoxybenzylidene)-1-phenylmethanamine 
• 74083-63-9 N-((3-methoxyphenyl)methylene)benzenemethanamine 
• 591-31-1 3-methoxy-benzaldehyde 
• 100-46-9 benzylamine 
• 1527-89-5 3-methoxybenzonitrile 
• 100-51-6 benzyl alcohol 
• 824-98-6 m-methoxybenzyl chloride 
• 100-47-0 benzonitrile 

Downstream Products

• 1309462-13-2 (6aS,12bS)-6-benzyl-1-methoxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine 
• 1309462-12-1 (6aS,12bS)-6-benzyl-3-methoxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine 
• 1309462-11-0 (6aS,12bS)-6-(3-methoxybenzyl)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine 
• 1309462-03-0 (1S,2S)-2-(benzyl(3-methoxybenzyl)amino)-1,2,3,4-tetrahydronaphthalen-1-ol 
• 1309462-47-2 (1S,2S)-2-(benzyl(3-methoxybenzyl)amino)-1,2-dihydronaphthalen-1-ol 
• 5120-75-2 N-benzyl-7-methoxy-1,2-dihydroisoquinolin-4(3H)-one 
• 620598-75-6 (S)-N-benzyl-N-(3-methoxybenzyl)-2-acetyloxy-2-phenylethanamide 
• 5077-15-6 ethyl N-(3-methoxybenzyl)benzylaminoethanoate 

Relevant articles and documents

The addition of amines to diisobutylaluminum-imine complexes. Preparation of NPS R-568 hydrochloride

A facile procedure for the preparation of secondary and tertiary amines from nitriles has been developed. The addition of amines to diisobutylaluminum-imine complexes derived by treating nitriles with DIBAL-H was found to proceed in moderate to good yield

Polyoxometalate-Driven Ease Conversion of Valuable Furfural to trans- N, N-4,5-Diaminocyclopenten-2-ones

We investigated the catalytic efficacy of silicotungstic acid (H4SiW12O40) polyoxometalate (POM) toward the reaction between furfural and amines that selectively yields trans-N,N-4,5-substituted-diaminocyclopenten-2-ones (trans-DACPs). H4SiW12O40 facilita

Ultrasound-assisted solventless synthesis of amines by in situ oxidation/reductive amination of benzyl halides

Ultrasound-assisted solventless oxidation/reductive amination of benzyl halides was developed as a facile, efficient, and environmental friendly method toward N-alkylated amines. Aldehydes were formed in situ by oxidation of organic halides with N-methylmorpholine N-oxide (NMO), followed by direct reductive amination with amines using sodium borohydride and montmorillonite K-10 catalyst as the reducing system. This green and simple procedure enables N-alkylated amines to be prepared in good to excellent yields with high selectivity of the monoalkylation. This journal is the Partner Organisations 2014.