134251-49-3Relevant academic research and scientific papers
Synthetic Studies on the Compounds Related to Neocarzinostatin Chromophore. 2. Synthesis of the Open-Chain (E)- and (Z)-Dienediyne Systems and Its Application to the Synthesis of an Strain-released Cyclic Analogue
Nakatani, Kazuhiko,Arai, Katsuko,Yamada, Kaoru,Terashima, Shiro
, p. 3045 - 3060 (2007/10/02)
The "double coupling " reaction of the (E)- and (Z)-dienol ditriflates (5 and 6) with various propargyl alcohols was found to give the (E)- and (Z)-dienediyne diols, the open-chain analogues of neocarzinostatin chromophore, stereospecifically.Those (E)- a
An expeditious synthesis of the open-chain (E)- and (Z)-dienediyne systems related to neocarzinostatine chromophore
Nakatani,Arai,Yamada,Terashima
, p. 3405 - 3406 (2007/10/02)
The title (E)- and (Z)-dienediyne systems could be successfully prepared by means of palladium-catalyzed double coupling reaction of (E)- and (Z)-dienolditriflates with various propargyl alcohols.
Palladium catalyzed couplings of enol triflates with alkynes under very mild conditions - The stereoselective synthesis of dienediynes from bis(enoltriflates)
Suffert,Bruckner
, p. 1453 - 1456 (2007/10/02)
The stereoselectivity accessible E-bis(enoltriflate) 6 couples under Pd(0)/CuI catalysis with two equiv. of alkyne giving E configuration dienediynes 7 with complete retention of stereochemistry.
