134259-05-5

Upstream product

• 80360-20-9 1-(phenylsulfonyl)indole-3-carbaldehyde 
• 96725-10-9 methyl 2-(2-bromo-2-propenylamino)acetate 
• 930-88-1 N-methylmaleimide 
• 134259-04-4 (1S,3S,3aR,6aS)-3-(1-Benzenesulfonyl-1H-indol-3-yl)-2-(2-bromo-allyl)-5-methyl-4,6-dioxo-octahydro-pyrrolo[3,4-c]pyrrole-1-carboxylic acid methyl ester 
• 134259-04-4 (1S,3S,3aS,6aR)-3-(1-Benzenesulfonyl-1H-indol-3-yl)-2-(2-bromo-allyl)-5-methyl-4,6-dioxo-octahydro-pyrrolo[3,4-c]pyrrole-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Sequential 1,3-dipolar cycloaddition-palladium catalysed cyclisation. A powerful new tactical combination

A new flexible tactical combination of a 1,3-dipolar cycloaddition of an in situ generated azomethine ylide followed by a palladium catalysed cyclisation is described. The two reactions can be carried out as a 1 pot procedure if desired. Four new stereoce