134259-34-0Relevant academic research and scientific papers
The Strain Limit in Intramolecular Nucleophilic Substitution
Jeffery, Stephen M.,Stirling, Charles J. M.
, p. 1617 - 1624 (2007/10/02)
Kinetics and products of reactions of sulfonyl-stabilised carbanions bearing ω-leaving groups have been examined.The intention was to explore the upper limit of strain that can be tolerated for intramolecular nucleophilic substitution in these systems and
Strain-induced Mechanism Change: the Limit of Strain Tolerance in Intramolecular Nucleophilic Substitution?
Jeffery, Stephen M.,Niedoba, Stefan,Stirling, Charles J. M.
, p. 650 - 652 (2007/10/02)
The limit of strain energy differential for intramolecular nucleophilic substitution via a sulfonyl-stabilised carbanion to give cyclopropane analogues in hydroxylic solvents is around 160 kJ mol-1; above this level, concerted, albeit unactivat
