134261-44-2Relevant academic research and scientific papers
Bis-heteroannulation. 15. Enantiospecific syntheses of (+)and (-)-norsecurinine
Jacobi, Peter A.,Blum, Charles A.,DeSimone, Robert W.,Udodong, Uko E. S.
, p. 5384 - 5392 (1991)
(-)-Norsecurinine (2a) has been prepared in a stereospecific fashion with the acetylenic oxazole 39 as the starting material. Diels-Alder cyclization of 39 afforded the furano ketone 45 that was transformed in five steps to the butenolide mesylate 52. Tra
TOTAL SYNTHESIS OF (+)- AND (-)-NORSECURININE
Jacobi, Peter A.,Blum, Charles A.,DeSimone, Robert W.,Udodong, Uko E. S.
, p. 7173 - 7176 (2007/10/02)
(-)-Norsecurinine (1a) has been prepared in a stereospecific fashion beginning with the acetylenic oxazole 18.Diels-Alder cyclization of 18 afforded the furanoketone 19, which was transformed in five steps to the butenolide mesylate 24.Transannular alkyla
