134261-49-7

Upstream product

• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 100-46-9 benzylamine 

Downstream Products

• 134261-50-0 (E)-N-Benzyl-N-(2-[1,3]dioxolan-2-yl-ethyl)-3-trimethylsilanyl-acrylamide 
• 1613464-86-0 (R)-quinuclidin-3-yl ((S)-(3-((4-((2-(1,3-dioxolan-2-yl)ethyl)(benzyl)carbamoyl)benzyl)oxy)phenyl)(phenyl)methyl)carbamate 
• 134261-54-4 (4aS,8S,8aR)-2-Benzyl-8-trimethylsilanyl-hexahydro-isoquinoline-1,6-dione 
• 134261-54-4 (4aR,8R,8aR)-2-Benzyl-8-trimethylsilanyl-hexahydro-isoquinoline-1,6-dione 
• 134261-62-4 Acetic acid 1-((3R,4S)-1-benzyl-3-vinyl-piperidin-4-ylmethyl)-2-(6-methoxy-quinolin-4-yl)-ethyl ester 
• 134261-58-8 Acetic acid 1-((3R,4S)-1-benzyl-3-vinyl-piperidin-4-ylmethyl)-2-quinolin-4-yl-ethyl ester 
• 134261-57-7 1-((3R,4S)-1-Benzyl-3-vinyl-piperidin-4-yl)-3-(6-methoxy-quinolin-4-yl)-propan-2-ol 
• 134261-53-3 (4aR,8R,8aS)-2-Benzyl-6-(tert-butyl-dimethyl-silanyloxy)-8-trimethylsilanyl-3,4,4a,5,8,8a-hexahydro-2H-isoquinolin-1-one 
• 134261-65-7 1-((3R,4S)-1-Benzyl-3-vinyl-piperidin-4-yl)-3-quinolin-4-yl-propan-2-ol 
• 134261-55-5 (4aR,9S,9aS)-2-Benzyl-9-trimethylsilanyl-hexahydro-7-oxa-2-aza-benzocycloheptene-1,6-dione 
• 134261-51-1 (E)-N-Benzyl-N-((E)-5-oxo-hex-3-enyl)-3-trimethylsilanyl-acrylamide 
• 134261-56-6 ((3R,4S)-1-Benzyl-2-oxo-3-vinyl-piperidin-4-yl)-acetic acid methyl ester 
• 134261-59-9 (E)-N-Benzyl-N-(3-oxo-propyl)-3-trimethylsilanyl-acrylamide 
• 134261-60-2 N-benzylmeroquinene aldehyde 

Relevant academic research and scientific papers

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

The present invention relates to compounds acting both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists, to processes for their preparation, to compositions comprising them, to therapeutic uses and combinations with other pharmaceutical active ingredients.

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

Compounds of formula (I) defined herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.