134265-82-0Relevant academic research and scientific papers
NITROAZINES. 12. REACTION OF 6-NITROAZOLOPYRIMIDINES WITH ACETONITRILES
Chupakhin, O. N.,Rusinov, V. L.,Tumashov, A. A.,Pilicheva, T. L.,Sidorov, E. O.,Karpin, I. V.
, p. 210 - 215 (2007/10/02)
Reaction of 6-nitroazolopyrimidines with cyanoacetamide, cyanoacetthioamide, or benzoylacetonitrile results in the conversion of the pyrimidine ring into a pyridine ring with the formation of 2-azolylamino-5-nitropyridines.Treatment of the latter with alcoholic sodium carbonate, or reaction of the azolopyrimidines with acetonitriles in an alkaline medium, affords 7-nitroazolopyridopyrimidines.
