134266-20-9

Upstream product

• 141-97-9 ethyl acetoacetate 
• 57-13-6 urea 
• 1761-61-1 5-bromosalicyclaldehyde 

Downstream Products

• 134266-23-2 4-(5-Bromo-2-hydroxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid hydrazide 
• 134266-26-5 Benzoic acid N'-[4-(5-bromo-2-hydroxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carbonyl]-hydrazide 
• 134266-25-4 4-(5-Bromo-2-hydroxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid N'-(2,4-dinitro-phenyl)-hydrazide 
• 134266-24-3 4-(5-Bromo-2-hydroxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid N'-phenyl-hydrazide 

Relevant academic research and scientific papers

Synthesis and antioxidative properties of some 3,4-dihydropyrimidin-2(1H) ones (-thiones)

3,4-Dihydropyrimidinones (-thiones) were prepared by ternary condensation of various aromatic aldehydes with ethyl acetoacetate and urea (thiourea) in the presence of trichloroacetic acid in ethanol. Pleiades Publishing, Inc., 2006.

Deep eutectic solvent mediated synthesis of 3,4-dihydropyrimidin-2(1H)-ones and evaluation of biological activities targeting neurodegenerative disorders

Substitution of hazardous and often harmful organic solvents with “green” and “sustainable” alternative reaction media is always desirous. Ionic liquids (IL) have emerged as valuable and versatile liquids that can replace most organic solvents in a variet

Design, Synthesis, and Antiviral activity of 1,2,3,4-Tetrahydropyrimidine derivatives acting as novel entry inhibitors to target at “Phe43 cavity” of HIV-1 gp120

The HIV-1 invasion is initiated with the interaction of viral glycoprotein gp120 and cellular receptor CD4. The binding mechanism reveals two major hotspots involved in gp120-CD4 interaction. The first one is a hydrophobic cavity (Phe43 cavity) on gp120 c

Solvent-free synthesis of monastrol derivatives catalyzed by NaHSO 4

(Chemical Equation Presented) Monastrol derivatives were synthesized by environment-friendly three component condensation reaction of salicylaldehyde analogues, b-ketoester, and urea or thiourea under solvent-free conditions with NaHSO4 as catalyst in hig