1342891-82-0

Basic information

• Product Name: diethyl 3-(4-nitrophenyl)-1-tosylaziridine-2,2-dicarboxylate
• Synonyms: diethyl 3-(4-nitrophenyl)-1-tosylaziridine-2,2-dicarboxylate
• CAS NO: 1342891-82-0
• Molecular Weight: 462.48
• Mol File: 1342891-82-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: diethyl 3-(4-nitrophenyl)-1-tosylaziridine-2,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 3-(4-nitrophenyl)-1-tosylaziridine-2,2-dicarboxylate(1342891-82-0)
• EPA Substance Registry System: diethyl 3-(4-nitrophenyl)-1-tosylaziridine-2,2-dicarboxylate(1342891-82-0)

Safety Data

• Hazardous Substances Data: 1342891-82-0(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 555-16-8 4-nitrobenzaldehdye 
• 13707-46-5 N-tosyl-4-nitrobenzaldimine 
• 685-87-0 Diethyl 2-bromomalonate 

Downstream Products

• 3585-95-3 3-(4-nitro-phenyl)-2-phenyl-oxaziridine 
• 1342891-90-0 diethyl 3-(4-methoxyphenyl)-5-(4-nitrophenyl)-1-tosyl-1H-pyrrole-2,2(5H)-dicarboxylate 
• 1342892-04-9 2,2-diethyl 4-methyl 5-(4-nitrophenyl)-3-(p-tolyl)-1-tosyl-1H-pyrrole-2,2,4(5H)-tricarboxylate 
• 1342892-03-8 diethyl 3-(4-methoxyphenyl)-5-(4-nitrophenyl)-4-phenyl-1-tosyl-1H-pyrrole-2,2(5H)-dicarboxylate 

Relevant articles and documents

TfOH-catalyzed formal [3+2] cycloaddition of N-tosylaziridine dicarboxylates and nitriles: Synthesis of tetrafunctionalized 2-imidazolines

We developed an efficient method for synthesis of tetrafunctionalized 2-imidazolines using TfOH-catalyzed formal [3+2] cycloaddition of N-tosylaziridine dicarboxylates and nitriles. This is the first report of C–N bond cleavage of N-tosylaziridine dicarboxylates catalyzed by Br?nsted acid and the reaction worked well over wide scope of substrates in good to excellent yields under mild conditions. The method has the potential to be applied to pharmaceutical design and synthesis of tetrafunctionalized 2-imidazolines.

Lewis Acid Catalyzed Annulation of Donor-Acceptor Cyclopropane and N-Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H-Furo[2,3-c]pyrroles

An efficient MgI2-catalyzed annulation between donor-acceptor cyclopropane and N-tosylaziridinedicarboxylate to access highly substituted 2H-furo[2,3-c]pyrrole bearing two rings and four stereocenters, including one quaternary carbon stereocent