1342894-78-3

Upstream product

• 95-48-7 ortho-cresol 
• 3328-73-2 4-hydroxy-5-methylisophthalaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 1342894-91-0 8-(3-(4-methoxyphenyl)-3-oxoprop-1-enyl),10-methyl-3,4-dihydro-2H,6H-3,6-epoxy-benzo[1,5]dioxocine 
• 1616108-75-8 (E)-3-(4-hydroxy-3-methyl-5-((E)-(thiazol-2-ylimino)methyl)phenyl)-1-(4-methoxy phenyl)prop-2-en-1-one 
• 1375171-52-0 (E)-6-((4-(7-chloroquinolin-4-ylamino)phenylamino)methylene)-4-((E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl)-2-methylcyclohexa-2,4-dienone 
• 1375171-42-8 (E)-6-((3-(7-chloroquinolin-4-ylamino)propylamino)methylene)-4-((E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl)-2-methylcyclohexa-2,4-dienone 
• 1375171-14-4 (E)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-4-((E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl)-2-methylcyclohexa-2,4-dienone 
• 1373497-71-2 (E)-3-(4-methoxyphenyl)-6-(3-(4-methoxyphenyl)-3-oxo-prop-1-enyl)-8-methyl-2H-chromen-2-one 

Relevant academic research and scientific papers

Highly efficient synthesis of chalcones from poly carbonyl aromatic compounds using bf3-et2o via a regioselective condensation reaction

A new, simple, highly efficient method for the synthesis of different types of carbonyl chalcones through a regioselective condensation reaction of appropriate 5-acetyl-2-hydroxybenzaldehyde with various substituted acetophenones and 4-hydroxyisothalaldehyde with various substituted aldehydes using BF3-Et2O as a reagent is described.

Synthesis and antifilarial activity of chalcone-thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi

Here we report the synthesis of novel chalcone-thiazole compounds and their antifilarial activity. The antifilarial properties of these hybrids were assessed against microfilariae as well as adult worms of Brugia malayi. Among all the synthesized compound

In vitro and in vivo antifilarial activity evaluation of 3,6-epoxy [1,5]dioxocines: A new class of antifilarial agents

A series of 3,6-epoxy [1,5]dioxocines were synthesized and evaluated for their antifilarial activity against adult parasites of human lymphatic filarial parasite Brugia malayi (sub-periodic strain) in vitro. Out of these, six compounds (4a-f) possessed im

Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores

A series of novel keto-enamine chalcone-chloroquine based hybrids were synthesized following new methodology developed in our laboratory. The synthesized compounds were screened against chloroquine sensitive strain (3D7) of Plasmodium falciparum in an in

Efficient and general synthesis of 3-aryl coumarins using cyanuric chloride 1

An efficient and general protocol for a rapid synthesis of different substituted 3-aryl coumarins is reported. A series of different substituted phenyl acetic acids have been successfully reacted with different substituted 2-hydroxy benzaldehydes in the presence of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and N-methyl morpholine to afford 3-aryl coumarins in good to excellent yields. Georg Thieme Verlag Stuttgart · New York.