13429-27-1

Usage

Uses

potassium myristate is a cleansing and emulsifying agent.

InChI:InChI=1/C14H28O2.K/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1

Upstream product

• 124-10-7 methyl myristoate 
• 544-63-8 n-tetradecanoic acid 

Downstream Products

• 20255-94-1 1,2-dimyristoyl-rac-glycerol 
• 7770-09-4 glycerol 1,3-dimyristate 
• 555-45-3 tritetradecanoylglycerol 
• 589-68-4 1-monoglyceride myristic acid 
• 22122-18-5 ethylene glycol monomyristate 
• 622-56-0 myristanilide 
• 60175-30-6 dilauryl-myristoyl-glycerol 
• 55256-01-4 1-Myristo-2-stearo-3-palmitin 
• 60138-19-4 1,2-distearoyl-3-myristoylglycerol 
• 7717-45-5 lead tetradecanoate 

Relevant academic research and scientific papers

Fatty acid potassium had beneficial bactericidal effects and removed Staphylococcus aureus biofilms while exhibiting reduced cytotoxicity towards mouse fibroblasts and human keratinocytes

Wounds frequently become infected or contaminated with bacteria. Potassium oleate (C18:1K), a type of fatty acid potassium, caused >4 log colony-forming unit (CFU)/mL reductions in the numbers of Staphylococcus aureus and Escherichia coli within 10 min and a >2 log CFU/mL reduction in the number of Clostridium difficile within 1 min. C18:1K (proportion removed: 90.3%) was significantly more effective at removing Staphylococcus aureus biofilms than the synthetic surfactant detergents sodium lauryl ether sulfate (SLES) (74.8%, p 0.01) and sodium lauryl sulfate (SLS) (78.0%, p 0.05). In the WST (water-soluble tetrazolium) assay, mouse fibroblasts (BALB/3T3 clone A31) in C18:1K (relative viability vs. control: 102.8%) demonstrated a significantly higher viability than those in SLES (30.1%) or SLS (18.1%, p 0.05). In a lactate dehydrogenase (LDH) leakage assay, C18:1K (relative leakage vs. control: 108.9%) was found to be associated with a significantly lower LDH leakage from mouse fibroblasts than SLES or SLS (720.6% and 523.4%, respectively; p 0.05). Potassium oleate demonstrated bactericidal effects against various species including Staphylococcus aureus, Escherichia coli, Bacillus cereus, and Clostridium difficile; removed significantly greater amounts of Staphylococcus aureus biofilm material than SLES and SLS; and maintained fibroblast viability; therefore, it might be useful for wound cleaning and peri-wound skin.

Continuous preparation method of metal fatty acid salt

The invention relates to a continuous preparation method of metal fatty acid salt. The continuous preparation method of the metal fatty acid salt comprises the step of continuously enabling fatty acidand metal hydroxides to react in a solvent and prepare the metal fatty acid salt in a microchannel reactor or pipeline reactor. The preparation method disclosed by the invention can control the particle diameter of a product material to be within 70nm and 1000nm, and the particle diameter of the product material can be adjusted as needed; the metal fatty acid salt is simple in preparation method,short in technological process, few in three wastes (waste water, waste residues and waste gas), beneficial to environmental protection and suitable for industrial production; the reactor used in theinvention has short reaction time, high safety, high efficiency and large productivity, and can realize continuous production, furthermore, the space utilization rate of workshops is high, and mass production can be realized; by adopting the preparation method disclosed by the invention, the solvent can be recycled to lower the production cost; and the preparation method has high conversion rateof raw materials, stable quality and high purity.

Base reactant

Alkyl nitriles in combination with alkali metal hydroxides provide super bases which are useful in various chemical processes.