134296-10-9Relevant academic research and scientific papers
Using Catalysts to Make Catalysts: Titanium-Catalyzed Hydroamination to Access P,N-Ligands for Assembling Catalysts in One Pot
Hao, Han,Bagnol, Thibault,Pucheault, Mathieu,Schafer, Laurel L.
supporting information, p. 1974 - 1979 (2021/04/05)
Using a diamido-bis(amidate) titanium precatalyst, the hydroamination of alkynylphosphines afforded phosphinoenamine products. After reduction, 2-aminophosphines are prepared in excellent yield and on gram scale. A broad variety of alkynylphosphines and primary amines with different electronic and steric features are tolerated in this sequential transformation, enabling the rapid assembly of a collection of ligands. Additionally, intermediate phosphinoenamines can be used directly as proligands for coordination to transition metals using protonolysis or salt metathesis reactions. These transformations result in easy-to-use one pot protocols to prepare metal P,N-complexes for catalysis or small molecule activation.
Scope and limitations of the preparation of aminophosphines R-NH(CH2CH2PPH2) and aminodiphosphines R-N(CH2CH2PPH2)2 via Michael addition of amines to vinylphosphines
Rahman,Steed,Hii
, p. 1320 - 1326 (2007/10/03)
The addition of a range of amines to vinyldiphenylphosphine oxide was examined under different reaction conditions. The methodology provides mixed phosphorus-nitrogen donor ligands R-NH(CH2CH2PPh2) 3 and R-N(CH2CH2PPh2)2 4, which could be prepared in high yields and purity in two simple steps. Labelling study revealed a non-concerted mechanism and the X-ray crystal structure of 1e is reported.
