134328-85-1

Basic information

• Product Name: 6,7-Dehydro-1α-hydroxyprevitamin D₃
• Synonyms: 6,7-Dehydro-1α-hydroxyprevitamin D₃
• CAS NO: 134328-85-1
• Molecular Weight: 398.629
• Mol File: 134328-85-1.mol

Chemical Properties

• CAS DataBase Reference: 6,7-Dehydro-1α-hydroxyprevitamin D₃(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-Dehydro-1α-hydroxyprevitamin D₃(134328-85-1)
• EPA Substance Registry System: 6,7-Dehydro-1α-hydroxyprevitamin D₃(134328-85-1)

Safety Data

• Hazardous Substances Data: 134328-85-1(Hazardous Substances Data)

Upstream product

• 116561-43-4 ((1R,3aR,7aR)-1-((R)-1,5-dimethylhexyl)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl) trifluoromethanesulfonate 
• 113375-51-2 (3S,5R)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene 
• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 66251-18-1 Grundmann's ketone 
• 4895-08-3 (1R,5R)-2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-methanol 
• 113375-47-6 (1R,2S,4R,6S)-2-Hydroxymethyl-1-methyl-4-(1-methylethenyl)-7-oxybicyclo<4.1.0>heptane 
• 113375-48-7 (1R,2S,4R,6S)-2-Hydroxymethyl-4-acetyl-1-methyl-7-oxabicyclo<4.1.0>heptane 
• 55448-87-8 (3S,5R)-3,5-Diacetoxy-2-methylcyclohex-1-ene-1-carboxaldehyde 
• 113393-82-1 Acetic acid (1S,5R)-5-acetoxy-3-(2,2-dibromo-vinyl)-2-methyl-cyclohex-2-enyl ester 
• 113375-49-8 (1R,2S,4R,6S)-2-Hydroxymethyl-4-acetoxy-1-methyl-7-oxabicyclo<4.1.0>heptane 
• 113375-50-1 (3S,5R)-5-Acetoxy-3-hydroxy-2-methylcyclohex-1-ene-1-carboxaldehyde 

Relevant articles and documents

Palladium-catalysed coupling of vinyl triflates with enynes and its application to the synthesis of 1α,25-dihydroxyvitamin D3

We describe a general approach, based on the palladium-catalysed coupling of enynes with vinyl triflates, for the construction of dienynes related to vitamin D metabolites and analogues. As an application of this method, an efficient convergent synthesis of 1α,25-dihydroxyvitamin D3 starting from the Inhoffen-Lythgoe diol (6a) and natural carvones has been carried out (11 steps, 28% overall yield from 6a). This strategy allows labelling of the side chain in the final steps of the synthesis.