13433-42-6

Basic information

• Product Name: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE
• Synonyms: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE;[(Trimethylsilyl)methyl]-phosphonic acid dimethyl ester
• CAS NO: 13433-42-6
• Molecular Formula: C₆H₁₇O₃PSi
• Molecular Weight: 196.26
• Mol File: 13433-42-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 111-114 °C21.5 mm Hg(lit.)
• Flash Point: 160 °F
• Appearance: /
• Density: 1.024 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.131mmHg at 25°C
• Refractive Index: n20/D 1.435(lit.)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE(13433-42-6)
• EPA Substance Registry System: DIMETHYL TRIMETHYLSILYLMETHYLPHOSPHONATE(13433-42-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 13433-42-6(Hazardous Substances Data)

Usage

General Description

Dimethyl Trimethylsilylmethylphosphonate is a chemical compound often utilized in scientific research and in some industrial applications. The name implies that it contains elements such as silicon, carbon, hydrogen, phosphorus, and oxygen in its molecular structure. Detailed information such as its molecular weight, boiling point, melting point, and flashpoint may vary based on the specific conditions under which the compound is formed or analyzed. Despite its complex name, all the information about its properties, uses, or safety measures are precisely recorded in chemical databases for the professionals who work with it. It's important to handle this chemical with care, given that its impact on human health and the environment is not thoroughly studied.

InChI:InChI=1/C6H17O3PSi/c1-8-10(7,9-2)6-11(3,4)5/h6H2,1-5H3

Upstream product

• 67-56-1 methanol 
• 13433-51-7 (trimethylsilanyl-methyl)-phosphonic acid-dichloride 
• 75-77-4 chloro-trimethyl-silane 
• 756-79-6 dimethyl methane phosphonate 
• 2344-80-1 Chloromethyltrimethylsilane 
• 121-45-9 phosphorous acid trimethyl ester 

Downstream Products

• 86000-94-4 dimethyl 2,2-diphenyl-2-(trimethylsiloxy)ethylphosphonate 
• 868-85-9 Dimethyl phosphite 
• 1015-28-7 dimethyl (2-oxo-2-phenylethyl)phosphonate 
• 104227-38-5 methyl 6-(dimethoxyphosphoryl)-5-oxohexanoate 
• 1615248-82-2 dmethyl (E)-2-(4-methylphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-83-3 dimethyl (Z)-2-(4-methylphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-81-1 dimethyl (E)-2-phenyl-1-(trimethylsilyl)vinylphosphonate 
• 1615248-85-5 dimethyl (Z)-2-(4-methoxyphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-84-4 dimethyl (E)-2-(4-methoxyphenyl)-1-(trimethylsilyl)vinylphosphonate 
• 1615248-95-7 (Z)-4-isopropenyl-1-(2-(dimethylphosphono)-2-(trimethylsilylvinyl))cyclohexene 
• 1615248-94-6 (E)-4-isopropenyl-1-(2-(dimethylphosphono)-2-(trimethylsilylvinyl))cyclohexene 
• 1615248-92-4 dimethyl (1E,3E)-4-(4-methoxyphenyl)-1-(trimethylsilyl)-1,3-butadienylphosphonate 
• 1615248-93-5 dimethyl (1Z,3E)-4-(4-methoxyphenyl)-1-(trimethylsilyl)-1,3-butadienylphosphonate 
• 538-58-9 1,5-diphenyl-1,4-pentadien-3-one 

Relevant articles and documents

Chemoselective synthesis of β-ketophosphonates using lithiated α-(trimethylsilyl)methylphosphonate

A highly chemoselective synthesis of β-ketophosphonates from pentafluorophenyl esters and lithiated methyl α-(trimethylsilyl)methylphosphonate has been developed. This mild lithiated phosphonate reagent allows the synthesis of functionalized β-ketophosphonates in the presence of unactivated esters with high yields. This method has been compared with the standard lithiated methylphosphonate reagent.

Fluoride Ion-Induced Horner-Emmons Reaction of α-Silylalkylphosphonic Derivatives with Carbonyl Compounds

Dimethyl α-trimethylsilylbenzylphosphonate was allowed to react with carbonyl compounds in the presence of fluoride ion to give the corresponding olefins in fairly good yields.Use of CsF in tetrahydrofuran gave the best result.On the other hand, dimethyl trimethylsilylmethylphosphonate was allowed to react similarly with benzophenone to afford 1,1-diphenylethylene, dimethyl methylphosphonate, and dimethyl 2,2-diphenylethenylphosphonate.A similar result was obtained by using O,O-diethyl trimethylsilylmethylphophonothioate.But, reaction of trimethylsilylmethylphosphonic bis(diethylamide) afforded only the protodesilylation product.

A New Route to Dialkyl 1-(Trimethylsilyl)- and 1-(Trimethylstannyl)-alkanephosphonates

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