134334-50-2

Upstream product

• 62024-36-6 5-chloro-4-oxopentanoic acid methyl ester 
• 53856-93-2 methyl 5-bromo-4-oxopentanoate 
• 90-04-0 2-methoxy-phenylamine 
• 134334-46-6 N-(7-Benzyl-1,4-dioxa-7-aza-spiro[4.5]dec-8-ylmethyl)-2-chloro-N-(2-methoxy-phenyl)-acetamide 
• 134334-42-2 1-Benzyl-5-(ethylenedioxy)-N-(2-methoxyphenyl)-2-piperidinemethanamine 
• 134334-44-4 7-(Ethylenedioxy)-2-(2-methoxyphenyl)octahydro-2H-pyrido<1,2-a>pyrazin-3-one 
• 134334-33-1 1-Benzyl-5-(ethylenedioxy)-2-piperidinecarboxaldehyde 
• 141856-25-9 Methyl 5-amino>-4-oxopentanoate 
• 141856-29-3 Methyl 5-amino>-4-oxopentanoate 
• 141856-24-8 N-(2-Methoxyphenyl)-N'-(triphenylmethyl)ethane-1,2-diamine 
• 141856-21-5 N-(Benzyloxycarbonyl)-N'-(2-methoxyphenyl)ethane-1,2-diamine 
• 141856-26-0 Methyl 4-(2-Methoxyphenyl)piperazin-2-ylpropionate 
• 36908-21-1 N¹-(2-methoxy-phenyl)-ethane-1,2-diamine 
• 141856-31-7 Methyl 2-Methoxycarbonylethyl-4-(2-methoxyphenyl)piperazin-1-ylacetate 

Relevant academic research and scientific papers

Synthesis of Lactam and Ketone Precursors of 2,7-Substituted Octahydropyrrolopyrazines and Octahydro-2H-pyridopyrazines

This report describes the synthesis of the hexahydropyrrolopyrazin-6(2H)-ones 6, the hexahydropyrrolopyrazin-7(6H)-ones 7, and the hexahydro-2H-pyridopyrazin-7(6H)-ones 8, precursors of 2,7-substituted octahydropyrrolo- and octahydro-

Synthesis of 2,5-Substituted Piperidines and Their Bicyclic Piperazine Analogues: The 2,7-Substituted Octahydro-2H-pyridopyrazines

Partial and complete reduction of the key compound 1-benzyl-5-(ethylenedioxy)-2-piperidinecarbonitrile (1) was applied to generate the corresponding aldehyde 2 and primary amine 3.These were transformed into bicyclic 7-(ethylenedioxy)-2(R)-octahydro-2H-py