1343479-90-2Relevant academic research and scientific papers
High-yield synthesis of pyrrolidinyl PNA monomers
Merino, Pedro,Greco, Graziella,Tejero, Tomás,Chiacchio, Ugo,Corsaro, Antonino,Pistarà, Venerando,Romeo, Giovanni
, p. 6003 - 6006 (2011)
Two monomers for the syntheses of conformationally restricted peptide nucleic acids were synthesized through a simple procedure, involving an asymmetric 1,3-dipolar cycloaddition chemistry as a key step, from common starting materials in 3 and 5 steps, and 58.8% and 30.5% overall yields, respectively.
