1343490-49-2Relevant academic research and scientific papers
One-pot regio- and stereoselective synthesis of α′-methoxy- γ-pyrones: Biological evaluation as mitochondrial respiratory complex inhibitors
Rosso, Helena,De Paolis, Michael,Collin, Valerie C.,Dey, Sriloy,Hecht, Sidney M.,Prandi, Cristina,Richard, Vincent,Maddaluno, Jacques
experimental part, p. 9429 - 9437 (2012/01/06)
The one-pot construction of functionalized α′-methoxy-γ- pyrones is detailed. Starting from α,α′-dimethoxy-γ- pyrone, molecular diversity is attained by a regio- and stereoselective desymmetrization using allyllithium followed by vinylogous aldol reaction
