134354-28-2

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 920-46-7 Methacryloyl chloride 

Downstream Products

• 1081979-52-3 N-(3,5-dimethoxyphenyl)-N,2-dimethylacrylamide 

Relevant academic research and scientific papers

Arylnitration of alkenes by nitration/C-H functionalization cascade using AgNO3 and HOAc

A novel arylnitration of alkenes by nitration and C-H functionalization cascade process has been developed. This methodology provides an efficient way to construct a variety of nitro-containing oxindoles and dihydroquinolin-2(1H)-ones. In addition, the process exhibits significant functional group tolerance. Moreover, the use of inexpensive and readily available starting materials makes this practical and atom-economical approach particularly attractive.

N-Heterocyclic Carbene-Catalyzed Truce-Smiles Rearrangement of N-Arylacrylamides via the Cleavage of Unactivated C(aryl)-N Bonds

We report on the N-heterocyclic carbene (NHC)-catalyzed Truce-Smiles rearrangement of aniline derivatives, in which an unactivated C(aryl)-N bond is cleaved, leading to the formation of a new C(aryl)-C bond. The key to the success of this reaction is the

Oxidant-Free Rhodium(I)-Catalyzed Difunctionalization of Acrylamide: An Efficient Approach to Synthesize Oxindoles

(Figure Presented) The first rhodium(I)-catalyzed difunctionalization of arylacrylamides to synthesize oxindoles is developed, and it does not require the assistance of an oxidant. This method provides an efficient approach to generate various useful functionalized oxindoles, some of which cannot be easily accessed by previous approaches.

Arylnitration of alkenes by nitration/C-H functionalization cascade using AgNO3 and HOAc

A novel arylnitration of alkenes by nitration and C-H functionalization cascade process has been developed. This methodology provides an efficient way to construct a variety of nitro-containing oxindoles and dihydroquinolin-2(1H)- ones. In addition, the process exhibits significant functional group tolerance. Moreover, the use of inexpensive and readily available starting materials makes this practical and atom-economical approach particularly attractive.

Metal-free carbonitration of alkenes using K2S2O 8

A novel metal-free oxidative carbonitration of alkenes by a nitration and C-H functionalization cascade process has been developed. This methodology provides an efficient way to construct valuable nitro-containing oxindoles.

Photochemical elimination of leaving groups from zwitterionic intermediates generated via electrocyclic ring closure of α,β-unsaturated anilides

(Chemical Equation Presented) Methacrylanilides, ArN(CH3) COC(CH2LG)=CH2, with allylic leaving groups (LG - = BocAla, PhCO2-, PhCH2CO 2-, PhO-) u