13436-57-2

Basic information

• Product Name: 1-(6-nitro-1H-indazol-1-yl)ethanone
• CAS NO: 13436-57-2
• Molecular Formula: C₉H₇N₃O₃
• Molecular Weight: 205.1702
• Mol File: 13436-57-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 403.7°C at 760 mmHg
• Flash Point: 198°C
• Density: 1.48g/cm³
• Vapor Pressure: 9.96E-07mmHg at 25°C
• Refractive Index: 1.683
• CAS DataBase Reference: 1-(6-nitro-1H-indazol-1-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-nitro-1H-indazol-1-yl)ethanone(13436-57-2)
• EPA Substance Registry System: 1-(6-nitro-1H-indazol-1-yl)ethanone(13436-57-2)

Safety Data

• Hazardous Substances Data: 13436-57-2(Hazardous Substances Data)

Usage

General Description

1-(6-nitro-1H-indazol-1-yl)ethanone is a chemical compound with the molecular formula C9H7N3O3. It is a yellow solid that is used in organic synthesis and pharmaceutical research. The compound contains a nitro group and an indazole ring, making it a potential candidate for drug development due to its interesting structural features. It is also a versatile building block for the synthesis of other biologically active compounds. Additionally, it has been studied for its potential pharmacological properties and may have applications in the development of new therapeutic agents. Overall, 1-(6-nitro-1H-indazol-1-yl)ethanone has potential uses in the field of medicinal chemistry and drug discovery.

Upstream product

• 13572-31-1 2-acetyl-6-nitro-2H-indazole 
• 99-55-8 2-methyl-5-nitroaniline 
• 108-24-7 acetic anhydride 
• 7597-18-4 6-nitroindazole 

Downstream Products

• 501653-37-8 1-(6-amino-1H-indazol-1-yl)ethanone 

Relevant articles and documents

N-indazole substituted thiourea derivatives and preparation method and application thereof

The invention discloses N-indazole substituted thiourea derivatives and a preparation method and application thereof and belongs to the technical field of chemical medicine.The thiourea derivatives are a series of compounds simultaneously containing the 1H-indazole ring structure and the asymmetrical thiourea structure, and the compounds are not reported in the literature.The bioactivity test result analysis of the thiourea derivatives show that the compounds are good in antioxidant activity, the average scavenging rate is above 80%, the scavenging rate of the compound 12b, the compound 12c, and the compound 12d and the compound 12h is higher than 90%, the scavenging activity IC50 of the compound 12h on DPPH is 0.14mg/mL; part of the target compounds has certain inhibition activity on herpes viruses, vaccinia viruses, reoviruses, Coxsackie viruses, Feline coronary herpes viruses, HIV viruses and the like, and the compound 12c and the compound 12n are high in antivirus activity; the synthesized compounds hopefully have new bioactivity which is not expounded, and a certain material basis is provided for the development of new medicine.

THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES

Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases