13436-57-2

Usage

Uses

Used in Organic Synthesis:
1-(6-nitro-1H-indazol-1-yl)ethanone is used as a building block for the synthesis of other biologically active compounds, leveraging its unique structural features to create new molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(6-nitro-1H-indazol-1-yl)ethanone is used as a candidate for drug development due to its interesting chemical properties. Its potential as a precursor in the synthesis of new therapeutic agents makes it a valuable asset in the discovery of novel medications.
Used in Medicinal Chemistry:
1-(6-nitro-1H-indazol-1-yl)ethanone is employed in medicinal chemistry for its potential pharmacological properties. Researchers are studying its interactions and effects to understand its role in the development of new therapeutic agents, particularly in the context of drug discovery and design.

Upstream product

• 13572-31-1 2-acetyl-6-nitro-2H-indazole 
• 99-55-8 2-methyl-5-nitroaniline 
• 108-24-7 acetic anhydride 
• 7597-18-4 6-nitroindazole 

Downstream Products

• 501653-37-8 1-(6-amino-1H-indazol-1-yl)ethanone 

Relevant academic research and scientific papers

N-indazole substituted thiourea derivatives and preparation method and application thereof

The invention discloses N-indazole substituted thiourea derivatives and a preparation method and application thereof and belongs to the technical field of chemical medicine.The thiourea derivatives are a series of compounds simultaneously containing the 1H-indazole ring structure and the asymmetrical thiourea structure, and the compounds are not reported in the literature.The bioactivity test result analysis of the thiourea derivatives show that the compounds are good in antioxidant activity, the average scavenging rate is above 80%, the scavenging rate of the compound 12b, the compound 12c, and the compound 12d and the compound 12h is higher than 90%, the scavenging activity IC50 of the compound 12h on DPPH is 0.14mg/mL; part of the target compounds has certain inhibition activity on herpes viruses, vaccinia viruses, reoviruses, Coxsackie viruses, Feline coronary herpes viruses, HIV viruses and the like, and the compound 12c and the compound 12n are high in antivirus activity; the synthesized compounds hopefully have new bioactivity which is not expounded, and a certain material basis is provided for the development of new medicine.

THIENO[3,2-D]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES

Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.

THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES

Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases