134362-19-9Relevant academic research and scientific papers
Convenient Approach to 2-Substituted (Thio)morpholin-3-ones from α-Diazoacetates via X-H Carbene Insertion – Lactamization Sequence
Solovyov, Igor,Dar'in, Dmitry,Krasavin, Mikhail
, p. 7432 - 7438 (2019)
Stepwise coupling of N-Boc-protected β-aminoethanols or β-mercaptoethylamines with various α-diazoacetates provides a new, unified approach to constructing (thio)morpholin-3-ones. The process involves a Rh2(esp)2-catalyzed X-H insert
METALLO-BETA-LACTAMASE INHIBITORS
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Page/Page column 184, (2017/04/04)
The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.
