13441-52-6Relevant academic research and scientific papers
Human tryptophan dioxygenase: A comparison to indoleamine 2,3-dioxygenase
Batabyal, Dipanwita,Yeh, Syun-Ru
, p. 15690 - 15701 (2007)
In contrast to the diverse superfamily of monooxygenases, there are only two classes of heme-containing dioxygenases in humans. One is tryptophan 2,3 dioxygenase (hTDO), and the other is indoleamine 2,3-dioxygenase (hIDO), both of which catalyze the oxida
Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1
Pantouris, Georgios,Serys, Martynas,Yuasa, Hajime J.,Ball, Helen J.,Mowat, Christopher G.
, p. 2155 - 2163 (2014)
Indoleamine 2,3-dioxygenase-2 (IDO2) is one of three enzymes (alongside tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase (IDO1)) that catalyse dioxygenation of l-tryptophan as the first step in the kynurenine pathway. Despite the reported expres
