1344115-22-5

Basic information

• Product Name: C₁₆H₁₆N₄O₂
• Synonyms: C₁₆H₁₆N₄O₂
• CAS NO: 1344115-22-5
• Molecular Weight: 296.329
• Mol File: 1344115-22-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₆N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₆N₄O₂(1344115-22-5)
• EPA Substance Registry System: C₁₆H₁₆N₄O₂(1344115-22-5)

Safety Data

• Hazardous Substances Data: 1344115-22-5(Hazardous Substances Data)

Upstream product

• 34000-31-2 2',4-dihydroxychalcone 
• 2582-30-1 aminoguanidine bicarbonate 

Relevant articles and documents

Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis

Mycobacterium tuberculosis (Mtb) and Yersinia pestis (Yp) produce siderophores with scaffolds of nonribosomal peptide-polyketide origin. Compounds with structural similarities to these siderophores were synthesized and evaluated as antimicrobials against Mtb and Yp under iron-limiting conditions mimicking the iron scarcity these pathogens encounter in the host and under standard iron-rich conditions. Several new antimicrobials were identified, including some with increased potency in the iron-limiting condition. Our study illustrates the possibility of screening compound libraries in both iron-rich and iron-limiting conditions to identify antimicrobials that may selectively target iron scarcity-adapted bacteria and highlights the usefulness of building combinatorial libraries of compounds having scaffolds with structural similarities to siderophores to feed into antimicrobial screening programs.