1344141-53-2Relevant academic research and scientific papers
Inhibition of c-KIT, VEGFR-2 (KDR), and ABCG2 by analogues of OSI-930
Patel, Jay P.,Kuang, Ye-Hong,Chen, Zhe-Sheng,Korlipara, Vijaya L.
, p. 6495 - 6499 (2011/12/21)
The quinoline domain of OSI-930, a dual inhibitor of receptor tyrosine kinases (RTKs) c-Kit and KDR, was modified in an effort to further understand the SAR of OSI-930, and the binding site characteristics of c-Kit and KDR. A series of 16 compounds with h
