134415-42-2 Usage
Uses
Used in Chemical Research:
4-BROMOCHLOROBENZENE-D4 is used as a research compound for studying chemical reactions and mechanisms. The deuterium labeling allows researchers to track the behavior of the molecule and observe the effects of isotopic substitution on reaction rates and product formation.
Used in Analytical Chemistry:
In analytical chemistry, 4-BROMOCHLOROBENZENE-D4 is used as an internal standard or a reference material. The presence of deuterium atoms provides a distinct signature in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, enabling accurate quantification and identification of target compounds.
Used in Pharmaceutical Development:
4-BROMOCHLOROBENZENE-D4 is employed in the development of pharmaceuticals as a potential drug candidate or as a tool to study the metabolism and pharmacokinetics of related compounds. The deuterium labeling can provide insights into the stability, bioavailability, and potential side effects of the compound.
Used in Environmental Studies:
In environmental science, 4-BROMOCHLOROBENZENE-D4 can be used to investigate the fate and transport of pollutants in the environment. The isotopically labeled compound can serve as a tracer, helping to understand the behavior of similar organic compounds in various environmental matrices.
Used in Material Science:
4-BROMOCHLOROBENZENE-D4 is utilized in material science research to study the properties of deuterated organic compounds. The incorporation of deuterium atoms can affect the physical and chemical properties of materials, such as their thermal stability, solubility, and electronic properties, which can be valuable for the development of new materials with specific characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 134415-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,4,1 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 134415-42:
(8*1)+(7*3)+(6*4)+(5*4)+(4*1)+(3*5)+(2*4)+(1*2)=102
102 % 10 = 2
So 134415-42-2 is a valid CAS Registry Number.
134415-42-2Relevant academic research and scientific papers
Deuterated polyhalogen aromatic compound and preparation method thereof, and organic intermediate
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Paragraph 0078-0094, (2021/07/24)
The invention discloses a perdeuterated polyhalogen aromatic compound and a preparation method thereof, and an organic intermediate. Cheap deuterium water is taken as a deuterated raw material, common toluene is taken as a solvent, silver salt is taken as
Synthesis of Multideuterated (Hetero)aryl Bromides by Ag(I)-Catalyzed H/D Exchange
Hu, Guang-Qi,Bai, Jing-Wen,Li, En-Ci,Liu, Kai-Hui,Sheng, Fei-Fei,Zhang, Hong-Hai
supporting information, p. 1554 - 1560 (2021/03/03)
Deterium-labeled (hetero)aryl bromide is one of the most widespread applicable motifs to achieve important deuterated architectures for various scientific applications. Traditionally, these deterium-labeled (hetero)aryl bromides are commonly prepared via multistep syntheses. Herein, we disclose a direct H/D exchange protocol for deuteration of (hetero)aryl bromides using Ag2CO3 as catalyst and D2O as deuterium source. This protocol is highly efficient, simply manipulated, and appliable for deuterium-labeling of over 55 (hetero)aryl bromides including bioactive druglike molecules and key intermediates of functional materials. In addition, this method showed distinguishing site-selectivity toward the existing transition-metal-catalyzed HIE process, leading to multideuterated (hetero)aryl bromides in one step.
