1344151-84-3Relevant academic research and scientific papers
Discovery of a novel series of cyclic urea as potent CCR5 antagonists
Duan, Maosheng,Kazmierski, Wieslaw M.,Tallant, Matt,Jun, Jung Ho,Edelstein, Mark,Ferris, Rob,Todd, Dan,Wheelan, Pat,Xiong, Zhiping
, p. 6381 - 6385 (2011/12/02)
A novel series of cyclic urea-based CCR5 antagonists was designed aiming to resolve instability issue in the fasted simulated intestinal fluid (FSIF) associated with the acyclic urea moiety in 1. This class of CCR5 compounds demonstrated high antiviral ac
