13442-89-2Relevant academic research and scientific papers
Electrophilic Addition to Alkoxyethenes. XV. Influence of Structure and Temperature on the Rate of Ethanol Addition
Nedolya, N. A.,Baranskii, V. A.,Trofimov, B. A.
, p. 287 - 290 (2007/10/03)
Rates of acid-catalyzed (in the presence of HCl) addition of ethanol to various alkyl vinyl ethers in the system cyclohexane-ethanol (4:1 by volume) have been measured at 10, 20, 25, 30, and 40 deg C.Linear regression equations have been found that adequately describe the influence of temperature and the substrate structure on the rate constant.The effect of the alkyl substituents includes variable contribution of the steric factor; bulky substituents facilitate the reaction.
WITTIG-HORNER REACTION IN HETEROGENOUS MEDIA VII. A NEW STRATEGY FOR THE TOTAL SYNTHESIS OF THE ROYAL JELLY ACID AND THE QUEEN SUBSTANCE OF HONEY-BEE
Villieras, J.,Rambaud, M.,Graff, M.
, p. 569 - 580 (2007/10/02)
A new general scheme for the preparation of Royal Jelly acid and Queen Substance of honey-bee, including, as the key steps, copper I catalyzed addition of functional (protected alcohol and ketone) Grignard reagents to acrolein diethylacetal, and the Wittig-Horner reaction of unprotected 8-hydroxyoctanal and 7-oxo-octanal with triethylphosphonoacetate in water, in the presence of potassium carbonate.
