134420-93-2

Basic information

• Product Name: ethyl 3-(benzylamino)valerate
• CAS NO: 134420-93-2
• Molecular Weight: 235.326
• Mol File: 134420-93-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 3-(benzylamino)valerate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(benzylamino)valerate(134420-93-2)
• EPA Substance Registry System: ethyl 3-(benzylamino)valerate(134420-93-2)

Safety Data

• Hazardous Substances Data: 134420-93-2(Hazardous Substances Data)

Upstream product

• 2445-93-4 ethyl 2-pentenoate 
• 100-46-9 benzylamine 
• 27805-84-1 (cis)-2-pentenoic acid ethyl ester 

Relevant articles and documents

Practical, highly enantioselective chemoenzymatic one-pot synthesis of short-chain aliphatic β-amino acid esters

A practical, highly enantioselective method for the synthesis of short-chain aliphatic β-amino acid esters was developed starting from prochiral and easily accessible substrates. This chemoenzymatic approach is based on a nonenzymatic aza-Michael addition

GABA-uptake inhibitors: Construction of a general pharmacophore model and successful prediction of a new representative

A model for the pharmacophore of GABA-uptake inhibitors was established using published structure-activity data and molecular modeling. The model accounted for the activities of different classes of GABA-uptake inhibitors. Analogues of guvacine substituted at position 6 were synthesized in order to confirm the model. 6-(3,3-Diphenylpropyl)guvacine (30f), which fit well with the pharmacophore, had an in vitro IC50 of 0.1 μM. This value is as good as those of the best GABA-uptake inhibitors known today.