134424-02-5

Basic information

• Product Name: 5'-O-benzyloxycarbonyl-2',3'-O-isopropylidene-5-fluorouridine
• Synonyms: 5'-O-benzyloxycarbonyl-2',3'-O-isopropylidene-5-fluorouridine
• CAS NO: 134424-02-5
• Molecular Weight: 436.394
• Mol File: 134424-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-benzyloxycarbonyl-2',3'-O-isopropylidene-5-fluorouridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-benzyloxycarbonyl-2',3'-O-isopropylidene-5-fluorouridine(134424-02-5)
• EPA Substance Registry System: 5'-O-benzyloxycarbonyl-2',3'-O-isopropylidene-5-fluorouridine(134424-02-5)

Safety Data

• Hazardous Substances Data: 134424-02-5(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 2797-17-3 2',3'-O-isopropylidene-5-fluorouridine 

Downstream Products

• 134424-03-6 5'-O-benzyloxycarbonyl-5-fluorouridine 

Relevant articles and documents

5-fluorouracil, 2'-deoxy-5-fluorouridine and 1-carbomoyl-5-fluorouracil compounds

A 5-fluorouracil derivative represented by the formula (1): STR1 wherein A represents a group represented by STR2 wherein R1 represents a hydrogen atom or OR5 group, R2, R3 and R5 may be the same or different and each represents a hydrogen atom or a group represented by the following formula (2): STR3 wherein R6 represents an acyl group, R7 represents a hydrogen atom, a straight or branched alkyl group, a cycloalkyl group, an aralkyl group, a lower alkenyl group or a phenyl group, and n is an integer of 0 to 6, provided that at least one of R2, R3 and R5 is a group represented by the formula (2), and the case wherein R2 and R5 are both hydrogen atoms is excluded, R4 represents a group represented by the formula (2), and X represents an alkylene group or a cycloalkylene group, and an antitumor agent containing the same as an active ingredient.