134431-55-3Relevant academic research and scientific papers
REACTIONS OF α-CHLOROIMINES WITH HOMOPHTHALIC ANHYDRIDES. SYNTHESIS AND MOLECULAR STRUCTURE OF 3,3a-DIHYDROFUROISOQUINOLINE-1,5(4H,9bH)-DIONES, FURO-8,9,16,16a-TETRAHYDRO-1H,3H,11H-DIBENZOQUINOLIZINE-1,11-DIONES AND RELATED COMPOUNDS
Georgieva, Angelina,Stanoeva, Elena,Spassov, Stefan,Macicek, Josef,Angelova, Olyana,et al.
, p. 3375 - 3388 (2007/10/02)
The reaction of α-chloroimines 1-3, resp. 11 with homophthalic anhydrides 4 leads to the formation of the isoquinoline ring system incorporated in furoisoquinolinediones 8-10, resp. 13a-(chloromethyl)-8H-dibenzo-quinolizine-8-one-13-carboxylic acids 12.The latter compounds were converted into furodibenzoquinolizinediones 13 under basic conditions.NMR studies provided information concerning the relative configuration and the solution conformation of the various heterocycles obtained.The molecular structure of 8b and 12b was determined by X-ray analysis.
