134432-16-9Relevant academic research and scientific papers
Alkylation of an imidazolidine enaminoester: A new sequence for the c(α)-alkylation of 4,5-dihydroimidazoles
Jones, Raymond C. F.,Patel, Pravin,Hirst, Simon C.,Turner, Ian
, p. 11781 - 11790 (2007/10/03)
1-Benzyl-2-(ethoxycarbonyllmethylene)-2,3,4,5-tetrahydroimidazole undergoes preferred C-alkylation with halogenonakanes, dihalogenoalkanes and epoxides: subsequent removal of of the ethoxycarbonyl group provides a new route to 2-alkyl-4,5-dihydroimidazoles. 1,3-Dihalogenoalkanes afford imidazo[1,2-a]pyridines via C,N-dialkylation.
A New Sequence for the Cα-Alkylation of 4,5-Dihydroimidazoles
Jones, Raymond, C. F.,Hirst, Simon C,Turner, Ian
, p. 953 - 954 (2007/10/02)
The C-alkylation of 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole with halogeno- and dihalogeno-alkanes is described; subsequent removal of the ethoxycarbonyl group provides a new route to 2-alkyl-4,5-dihydroimidazoles. 1,3-Dihalogenoalkanes afford imidazopyridines.
