134450-56-9

Usage

Uses

Used in the Chemical Industry:
4,5-Difluorophthalonitrile is used as an intermediate in the synthesis of various organic compounds, particularly in the preparation of benzo[g]pteridine. This application is significant because benzo[g]pteridine serves as an organic electron transfer mediator, which plays a crucial role in facilitating electron transfer processes in chemical reactions and materials science.
In the context of the provided materials, 4,5-Difluorophthalonitrile is specifically utilized in the preparation of benzo[g]pteridine, which is an organic electron transfer mediator. This application highlights the importance of 4,5-Difluorophthalonitrile in the chemical industry, where it contributes to the development of novel materials and compounds with potential applications in various fields, such as electronics, energy storage, and pharmaceuticals.

InChI:InChI=1S/C8H2F2N2/c9-7-1-5(3-11)6(4-12)2-8(7)10/h1-2H

Upstream product

• 557-21-1 zinc(II) cyanide 
• 64695-78-9 1,2-difluoro-4,5-dibromobenzene 

Downstream Products

• 1259331-73-1 4,5-di(2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranosyl)phthalonitrile 
• 1259331-72-0 4,5-di(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)phthalonitrile 
• 1259331-74-2 4,5-di(2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)phthalonitrile 
• 1416881-50-9 1,2‐bis(carbazol‐9‐yl)‐4,5‐dicyanobenzene 
• 18959-31-4 4,5-difluorophthalic acid 

Relevant academic research and scientific papers

Preparation method of 4, 5-difluorophthalic acid

The invention discloses a preparation method of 4, 5-difluorophthalic acid. The specific method comprises the following steps: S1: synthesis of 4, 5-difluoro-1, 2-phthalonitrile: adding 4, 5-difluoro-1, 2-dihalobenzene and polymethylhydrosiloxane into a reaction container, stirring and dissolving with N, N-dimethylacetamide, carrying out reaction, cooling after the reaction is finished, adding tri(dibenzylideneacetone)dipalladium and 1, 1 '-bis (diphenylphosphine) ferrocene under the protection of nitrogen, slowly adding zinc cyanide for reaction, cooling after the reaction is finished, adding water, adjusting the pH to 8 by using a sodium bicarbonate solution under vigorous stirring, stirring for 2 hours, standing, filtering, washing, and eluting and purifying by using an ethyl acetate mixed solvent of petroleum ether to obtain an off-white solid intermediate 4, 5-difluoro-1, 2-dicyanobenzene; and S2, synthesis of 4, 5-difluoro-1, 2phthalic acid. The process is safe, efficient, easy to operate, low in equipment requirement, low in raw material cost and easy for industrial production.

Preparation method of aromatic dicarboxylic acid derivative

The invention provides a preparation method of an aromatic dicarboxylic acid derivative, wherein the preparation method comprises the following steps: step 1, carrying out a coupling reaction on dihalogenated aromatic hydrocarbon and metal cyanide at a temperature of 40-200 DEG C under metal catalysis in a solvent, and carrying out extraction layering concentration to obtain a dicyano compound after the reaction is finished; and step 2, carrying out a hydrolysis reaction on the obtained dicyanogen compound at the temperature of 60-200 DEG C under an acidic condition, and carrying out post-treatment to obtain the final product. According to the preparation method of the aromatic dicarboxylic acid derivative, dihalogenated aromatic hydrocarbon reacts with metal cyanide and then is hydrolyzedunder the acidic condition to obtain aromatic acid or the derivative thereof, and the preparation method has the remarkable advantages that the raw materials are cheap and easy to obtain, operation is easy and convenient, the yield is high, three wastes are easy to dispose, the product quality is high, and the substrate tolerance is good.

DOPANT FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE

The present invention relates to: a dopant for an organic optoelectronic device, represented by chemical formula 1; an organic optoelectronic device including the dopant; and a display device.

Synthesis of phthalonitriles using a palladium catalyst

An easy synthetic method to obtain phthalonitriles from o-dibromobenzenes under mild conditions in high yields using Zn(CN)2 and a catalytic amount of tris(dibenzylideneacetone)dipalladium and 1,1′- bis(diphenylphosphino)ferrocene is described. Georg Thieme Verlag Stuttgart.