1344681-53-3

Upstream product

• 59748-90-2 4-Bromo-2-chloro-benzoic Acid 
• 1344681-59-9 5-bromo-3-chloro-3',5'-dimethyl-[1,1'-biphenyl]-2-carboxylic acid 

Relevant academic research and scientific papers

Carboxylic acids as traceless directing groups for formal meta-selective direct arylation

Without a trace: The first meta-selective direct C-H arylation that uses iodoarenes as coupling partners is reported (see scheme, EWG=electron- withdrawing group). This process utilizes carboxylic acid units as temporary directing groups that are cleaved during the reaction, leaving no trace in the resulting biaryl products.