1344705-66-3Relevant academic research and scientific papers
Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation
Mas-Moruno, Carlos,Beck, Johannes G.,Doedens, Lucas,Frank, Andreas O.,Marinelli, Luciana,Cosconati, Sandro,Novellino, Ettore,Kessler, Horst
, p. 9496 - 9500 (2011)
A subtle change: Structural changes upon amide bond methylation improve the selectivity of the anti-angiogenic drug Cilengitide, which after N-methylation at distinct positions discriminates between the closely related pro-angiogenic integrins αvβ3 and αv
