1344707-91-0

Upstream product

• 1120-71-4 1,3-propanesultone 
• 623-24-5 1,4-bis(bromomethyl)benzene 

Downstream Products

• 1357260-09-3 tetrabutylammonium 1-{4-[(2,2-dioxido-1,2-oxathiolan-3-yl)methyl]phenyl}-4-[(18F)]fluorobutane-2-sulfonate 
• 1344707-96-5 tetrabutylammonium 1-{4-[4-(ethylamino)-2-sulfobutyl]phenyl}-4-fluorobutane-2-sulfonate 
• 1344707-99-8 tetrabutylammonium 1-(4-{4-[(5-amino-5-carboxypentyl)amino]-2-sulfobutyl}phenyl)-4-fluorobutane-2-sulfonate 
• 1357260-05-9 tetrabutylammonium 1-{4-[4-(ethylamino)-2-sulfobutyl]phenyl}-4-[⁽¹⁸⁾F]fluorobutane-2-sulfonate 
• 1357259-96-1 tetrabutylammonium 1-(4-{4-[(5-amino-5-carboxypentyl)amino]-2-sulfobutyl}phenyl)-4-[⁽¹⁸⁾F]fluorobutane-2-sulfonate 
• 1344707-94-3 tetrabutylammonium 1-{4-[(2,2-dioxido-1,2-oxathiolan-3-yl)methyl]phenyl}-4-fluorobutane-2-sulfonate 

Relevant academic research and scientific papers

Sultone opening with [18F]fluoride: An efficient 18F-labelling strategy for PET imaging

Sultones were subject to ring opening by nucleophilic attack with [ 18F]fluoride to afford easily purified 18F-labelled hydrophilic sulfonated products in high yields. A two-step sequence including radiofluorination and coupling to l