134481-23-5

Upstream product

• 134481-25-7 2,2,2-Trifluoro-N-p-tolyl-acetimidoyl iodide 
• 536-74-3 phenylacetylene 
• 126855-72-9 N-(4-methylphenyl)-2,2,2-trifluoroacetimidoyl chloride 

Downstream Products

• 1111327-14-0 3-iodo-6-methyl-4-phenyl-2-(trifluoromethyl)quinoline 
• 1111327-44-6 (3-phenyl-1-trifluoromethyl-prop-2-ynyl)-p-tolylamine 
• 1282609-58-8 3-(diphenylmethylene)-5-methyl-2-(trifluoromethyl)-3H-indole 

Relevant academic research and scientific papers

Synthesis of highly substituted 2-perfluoroalkyl quinolines by electrophilic iodocyclization of perfluoroalkyl propargyl imines/amines

A series of highly substituted 2-perfluoroalkyl-3-iodoquinolines are prepared by two different methods in good to excellent yields under mild reaction conditions. The first method involves iodocyclization of perfluoroalkyl propargyl imines with I2/s

Palladium-catalyzed coupling reactions of trifluoroacetimidoyl iodides with olefins and 1-alkynes

Palladium-catalyzed coupling of trifluoroacetimidoyl iodides with olefins and 1-alkynes affords trifluoromethylated α-β-unsaturated imines, which are transformed into nitrogen heterocycles bearing CF3-group.