134484-37-0

Basic information

• Product Name: (R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL
• Synonyms: (S)-(-)-2-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL;(S)-2-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL;(S)-(-)-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL;(R)-(+)-2,-Diphenylphosphino-2'-methoxy-1,1'-biNAphthyll
• CAS NO: 134484-37-0
• Molecular Formula: C₃₃H₂₅O₂P
• Molecular Weight: 468.52
• Mol File: 134484-37-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL(134484-37-0)
• EPA Substance Registry System: (R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL(134484-37-0)

Safety Data

• Hazardous Substances Data: 134484-37-0(Hazardous Substances Data)

Usage

General Description

(R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL is a chiral ligand used in asymmetric catalysis. It is commonly used in the synthesis of pharmaceuticals and fine chemicals. The compound is known for its ability to efficiently catalyze a wide range of reactions, including hydrogenation, hydroformylation, and allylic alkylation. Its unique structure and stereochemistry make it a valuable tool in the field of organic synthesis, and it has been widely studied for its potential applications in the pharmaceutical industry. Additionally, the compound is considered to be environmentally friendly, as it is biodegradable and non-toxic, making it an attractive option for industrial applications.

Upstream product

• 161053-46-9 (S)-(-)-2-methoxy-2'-diphenylphosphino-1,1'-binaphthyl 
• 13922-41-3 1-Naphthylboronic acid 
• 1589518-11-5 (1-bromonaphthalen-2-yl)diphenylphosphine oxide 
• 74-88-4 methyl iodide 
• 602-09-5 1,1'-bi-2-naphthol 
• 4559-70-0 Diphenylphosphine oxide 
• 141807-44-5 (+/-)-2,2'-bis(trifluoromethanesulfonyloxy)-1,1-binaphthyl 
• 132532-04-8 (R)-2-diphenylphosphinyl-2'-trifluoromethanesulfonyloxy-1,1'-binaphthalene 
• 2216-69-5 1-Methoxynaphthalene 
• 1079-66-9 chloro-diphenylphosphine 
• 134484-35-8 (S)-2-iodo-2'-methoxy-1,1'-binaphthyl 
• 80317-69-7 2’-methoxy-(1,1’-binaphthyl)-2-carboxylic acid 
• 116741-62-9 (aS)-2'-methoxy-1,1'-binaphthyl-2-carbonyl chloride 
• 425687-39-4 (+/-)-2-amino-2'-methoxy-1,1'-binaphthyl 

Downstream Products

• 161053-46-9 (S)-(-)-2-methoxy-2'-diphenylphosphino-1,1'-binaphthyl 

Relevant articles and documents

Axially Chiral Biaryl Monophosphine Oxides Enabled by Palladium/WJ-Phos-Catalyzed Asymmetric Suzuki-Miyaura Cross-coupling

A highly enantioselective palladium/WJ-Phos-catalyzed Suzuki-Miyaura coupling reaction for efficient construction of axially chiral biaryl monophosphine oxides was developed. A series of axially chiral biaryl monophosphine oxides were obtained in good yields and with high enantioselectivities. The practicability of this reaction was validated in the straightforward synthesis of axially chiral biaryl monophosphine ligand and demonstrated by a 100-g-scale synthesis. Moreover, various functionalizations of the product make it as a platform molecule for synthesis of other chiral biaryl phosphines.

Nucleophilic aromatic substitution reactions of 1-methoxy-2- (diphenylphosphinyl)naphthalene with C-, N-, and O-nucleophiles: Facile synthesis of diphenyl(1-substituted-2-naphthyl)phosphines

A novel nucleophilic aromatic substitution reaction is described in which the methoxy group of 1-methoxy-2-(diphenylphosphinyl)-naphthalene is readily replaced with Grignard reagents, alkoxides, and amides. Reduction of the resulting phosphine oxides provides a convenient route to diphenyl(1- substituted-2-naphthyl)phosphines.

Catalytic Asymmetric Synthesis of Optically Active 2-Alkanols via Hydrosilylation of 1-Alkenes with a Chiral Monophosphine-Palladium Catalyst

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