1344980-53-5Relevant academic research and scientific papers
An efficient and recyclable catalyst for the cleavage of tert-butyldiphenylsilyl ethers
Yan, Shiqiang,Ding, Ning,Zhang, Wei,Wang, Peng,Li, Yingxia,Li, Ming
, p. 6 - 20 (2012/07/13)
An efficient, chemoselective, and environment-friendly method for the deprotection of tert-butyldiphenylsilyl ethers mediated by triflic acid supported on silica gel is reported. A wide range of tert-butyldiphenylsilyl ethers derived from carbohydrate and saponin residues can be smoothly cleaved in the presence of various types of other protecting groups in good to excellent yields in acetonitrile. This heterogeneous reaction does not require aqueous workup, and the supported catalyst can be readily recycled.
Highly efficient and mild method for regioselective de-O-benzylation of saccharides by Co2(CO)8-Et3SiH-CO reagent system
Yin, Zhao-Jun,Wang, Bo,Li, Yang-Bing,Meng, Xiang-Bao,Li, Zhong-Jun
supporting information; experimental part, p. 536 - 539 (2010/05/02)
[Chemical equation presented] A highly efficient and mild method for the de-O-benzylation of protected saccharides was developed by transforming terminal benzyl ethers Into silyl ethers using Co2(CO)8-Et 3SIH under 1 atm of CO. The method was successfully used for the de-O-benzylatlon of perbenzylated monosaccharides with various anomerlc protecting groups, as well as natural disaccharldes and trisaccharides such as sucrose, raffinose, and melezltose In good yields (>80%).
