1344995-07-8

Upstream product

• 1344995-05-6 5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-3-(((2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one 
• 6272-45-3 (E)-4-benzyloxycinnamic acid 

Relevant academic research and scientific papers

Synthesis of quercetin 3-O-[6"-O-(trans-p-coumaroyl)]-β-D- Glucopyranoside

This report describes the efficient synthesis of quercetin 3-O-[6"-O-(trans-pcoumaroyl)]- β-D-glucopyranoside 1 (isoquercitrin coumarate), an acylated quercetin glycoside possessing antihypertensive, antidiabetic, and tyrosinase inhibitory activities. The synthesis is initiated from commercially available quercetin via regioselective benzylation of quercetin to produce 4', 7-di-O-benzylquercetin (4). Through 4, 1 was successfully achieved via selective β-glycosylation of the 3-OH, acylation of 6"-OH, and finally debenzylation via catalytic transfer hydrogenation. Taylor & Francis Group, LLC.

Synthesis and antiradical activity of isoquercitrin esters with aromatic acids and their homologues

Isoquercitrin, (IQ, quercetin-3-O-β-D-glucopyranoside) is known for strong chemoprotectant activities. Acylation of flavonoid glucosides with carboxylic acids containing an aromatic ring brings entirely new properties to these compounds. Here, we describe